胡琼

作者: 时间:2021-03-16 点击数:

胡琼 博士 副教授 硕士生导师 广州市青年后备人才

(招生:化学学硕、材料与化工专硕)

广州市传感材料与器件重点实验室&广州大学分析科学技术研究中心

广州大学3003必赢贵宾会官方网址

广东省广州市番禺区大学城外环西路230号

Tel/Wechat:15850560755

E-mailq.hu@gzhu.edu.cn, q.hu@njust.edu.cn

https://www.researchgate.net/profile/Qiong_Hu13

 

教育及工作经历

2020/11-至今,广州大学3003必赢贵宾会官方网址,广州市传感材料与器件重点实验室&广州大学分析科学技术研究中心,副教授

2018/07-2020/10,广州大学3003必赢贵宾会官方网址,博士后研究员(合作导师:牛利教授)

2013/09-2018/06,南京理工大学环境与生物工程学院,生物化工,工学博士(导师:张学记教授、孔金明教授)

2009/09-2013/07,南京理工大学环境与生物工程学院,生物工程,工学学士

 

荣誉与学术兼职

(1) 广州大学2020年“年度学术新锐”

(2) MDPI旗下期刊Chemosensors客座编辑

(3) 广东省精准医学应用学会分子影像分会会员

本科教学

(1)《超分子化学》,专业选修课

(2)《超分子材料》,专业选修课

(3)《化学基础概论》,通识类选修课

(4)《无机及分析化学》,专业必修课

 

研究兴趣

(1) 电化学生物传感

(2) 生物分析与可视化检测

(3) 药物分析与精准医疗

(4) 肿瘤标志物早期诊断

(5) 即时检验与体外诊断

(6) 新型信号放大策略

(7) 可控/“活性”自由基聚合

 

科研项目

(1) 国家自然科学基金青年科学基金项目,25万,在研,主持

(2) 广东省自然科学基金面上项目,10万,在研,主持

(3) 广州市基础与应用基础研究项目,5.0万,在研,主持

(4) 广州市市校(院)联合资助基础与应用基础研究项目,20万,在研,主持

(5) 广州大学科研启动经费,15万,已结题,主持

(6) 广州市博士后科研项目资助经费,20万,已结题,主持

(7) 中国博士后科学基金第64批面上资助,5.0万,已结题,主持

(8) 国家自然科学基金面上项目,64万,在研,主要参与人

(9) 国家自然科学基金面上项目,65万,已结题,主要参与人

(10) 国家自然科学基金青年科学基金项目,25万,已结题,主要参与人

(11) 国家自然科学基金委员会科学部主任基金,10万,已结题,主要参与人

(12) 广东省重点领域研发计划项目,1000万,已结题,参与

 

指导大学生创新训练项目

(1) 2021年大学生创新训练项目,省级,0.6万,在研

(2) 2022年大学生创新训练项目,国家级,1.0万,在研

 

文章与专利

(1) Hu Q, Wang Q, Sun G, Kong J*, Zhang X*. Electrochemically mediated surface-initiated de novo growth of polymers for amplified electrochemical detection of DNA. Anal. Chem., 2017, 89, 9253-9259. (TOP期刊)

(2) Hu Q, Han D, Gan S*, Bao Y, Niu L*. Surface-initiated-reversible-addition–fragmentation-chain-transfer polymerization for electrochemical DNA biosensing. Anal. Chem., 2018, 90, 12207-12213. (TOP期刊)

(3) Hu Q, Kong J*, Han D, Zhang Y*, Bao Y, Zhang X, Niu L*. Electrochemically controlled RAFT polymerization for highly sensitive electrochemical biosensing of protein kinase activity. Anal. Chem., 2019, 91, 1936-1943. (TOP期刊)

(4) Hu Q, Bao Y, Gan S, Zhang Y*, Han D, Niu L. Amplified electrochemical biosensing of thrombin activity by RAFT polymerization. Anal. Chem., 2020, 92, 3470-3476. (TOP期刊)

(5) Hu Q, Gan S, Bao Y, Zhang Y*, Han D, Niu L. Electrochemically controlled ATRP for cleavage-based electrochemical detection of the prostate-specific antigen at femtomolar level concentrations. Anal. Chem., 2020, 92, 15982-15988. (TOP期刊)

(6) Hu Q, Su L, Chen Z, Huang Y, Qin D, Niu L*. Coenzyme-mediated electro-RAFT polymerization for amplified electrochemical interrogation of trypsin activity. Anal. Chem., 2021, 93, 9602-9608. (TOP期刊)

(7) Hu Q*, Su L, Luo Y, Cao X, Hu S, Li S, Liang Y, Liu S, Xu W, Qin D, Niu L*. Biologically mediated RAFT polymerization for electrochemical sensing of kinase activity. Anal. Chem., 2022, 94, 6200-6205. (TOP期刊)

(8) Hu Q*, Hu S, Li S, Liu S, Liang Y, Cao X, Luo Y, Xu W, Wang H, Wan J, Feng W, Niu L*. Boronate affinity-based electrochemical aptasensor for point-of-care glycoprotein detection. Anal. Chem., 2022, 94, 10206-10212. (TOP期刊)

(9) Hu Q*, Wan J, Wang H, Cao X, Li S, Liang Y, Luo Y, Wang W*, Niu L*. Boronate-affinity crosslinking-based ratiometric electrochemical detection of glycoconjugates. Anal. Chem., 2022, 94, 9481-9486. (TOP期刊)

(10) Hu Q*, Wan J, Luo Y, Li S, Cao X, Feng W, Liang Y, Wang W*, Niu L*. Electrochemical detection of femtomolar DNA via boronate affinity-mediated decoration of polysaccharides with electroactive tags. Anal. Chem., 2022, 94, 12860-12865. (TOP期刊)

(11) Hu Q*, Cao X, Li S, Liang Y, Luo Y, Feng W, Han D*, Niu L. Electrochemically controlled atom transfer radical polymerization for electrochemical aptasensing of tumor biomarkers. Anal. Chem., 2022, 94, 13516-13521. (TOP期刊)

(12) Hu Q, Hu W, Kong J*, Zhang X*. Ultrasensitive electrochemical DNA biosensor by exploiting hematin as efficient biomimetic catalyst toward in situ metallization. Biosens. Bioelectron., 2015, 63, 269-275. (TOP期刊)

(13) Hu Q, Deng X, Yu X, Kong J*, Zhang X*. One-step conjugation of aminoferrocene to phosphate groups as electroactive probes for electrochemical detection of sequence-specific DNA. Biosens. Bioelectron., 2015, 65, 71-77. (TOP期刊)

(14) Hu Q, Wang Q, Kong J*, Li L, Zhang X*. Electrochemically mediated in situ growth of electroactive polymers for highly sensitive detection of double-stranded DNA without sequence-preference. Biosens. Bioelectron., 2018, 101, 1-6. (TOP期刊)

(15) Hu Q, Wang Q, Jiang C, Zhang J, Kong J*, Zhang X*. Electrochemically mediated polymerization for highly sensitive detection of protein kinase activity. Biosens. Bioelectron., 2018, 110, 52-57.

(16) Hu Q, Bao Y, Gan S, Zhang Y*, Han D, Niu L*. Electrochemically controlled grafting of polymers for ultrasensitive electrochemical assay of trypsin activity. Biosens. Bioelectron., 2020, 165, 112358. (TOP期刊)

(17) Hu Q, Su L, Mao Y, Gan S, Bao Y, Qin D, Wang W*, Zhang Y, Niu L*. Electrochemically induced grafting of ferrocenyl polymers for ultrasensitive cleavage-based interrogation of matrix metalloproteinase activity. Biosens. Bioelectron., 2021, 178, 113010. (TOP期刊)

(18) Hu Q*, Luo Y, Cao X, Chen Z, Huang Y, Niu L*. Bioinspired electro-RAFT polymerization for electrochemical sensing of nucleic acids. ACS Appl. Mater. Interfaces, 2021, 13, 54794-54800. (TOP期刊)

(19) Hu Q, Kong J*, Han D, Niu L*, Zhang X*. Electrochemical DNA biosensing via electrochemically controlled reversible addition–fragmentation chain transfer polymerization. ACS Sens., 2019, 4, 235-241. (TOP期刊)

(20) Hu Q, Su L, Huang Y, Chen Z, Cao X, Luo Y, Qin D, Niu L*. Coenzyme-mediated electro-grafting for ultrasensitive electrochemical DNA biosensing. Sens. Actuators, B, 2021, 346, 130551. (TOP期刊)

(21) Hu Q, Kong J*, Li Y, Zhang X*. A signal-on electrochemical DNA biosensor based on potential-assisted Cu(I)-catalyzed azide-alkyne cycloaddition mediated labeling of hairpin-like oligonucleotide with electroactive probe. Talanta, 2016, 147, 516-522.

(22) Hu Q, He M, Mei Y, Feng W, Jing S, Kong J*, Zhang X*. Sensitive and selective colorimetric assay of alkaline phosphatase activity with Cu(II)-phenanthroline complex. Talanta, 2017, 163, 146-152.

(23) Hu Q, Ma K, Mei Y, He M, Kong J*, Zhang X*. Metal-to-ligand charge-transfer: Applications to visual detection of β-galactosidase activity and sandwich immunoassay. Talanta, 2017, 167, 253-259.

(24) Hu Q, Kong J*, Han D, Bao Y, Zhang X*, Zhang Y*, Niu L. Ultrasensitive peptide-based electrochemical detection of protein kinase activity amplified by RAFT polymerization. Talanta, 2020, 206, 120173.

(25) Hu Q, Li L, Sun G, Li D, Kong J*, Huang W, Zhang X*. 5-Carboxyfluorescein: Intrinsic peroxidase-like catalytic activity and its application in the biomimetic synthesis of polyaniline nanoplatelets. J. Mater. Chem. B, 2017, 5, 5937-5941.

(26) Hu Q, Gan S, Bao Y, Zhang Y, Han D, Niu L*. Controlled/“living” radical polymerization-based signal amplification strategies for biosensing. J. Mater. Chem. B, 2020, 8, 3327-3340. (Invited Review)

(27) Hu Q, Zhou B, Dang P, Li L, Kong J*, Zhang X*. Facile colorimetric assay of alkaline phosphatase activity using Fe(II)-phenanthroline reporter. Anal. Chim. Acta, 2017, 950, 170-177.

(28) Hu Q, Hu W, Kong J*, Zhang X*. PNA-based DNA assay with attomolar detection limit based on polygalacturonic acid mediated in-situ deposition of metallic silver on a gold electrode. Microchim. Acta, 2015, 182, 427-434.

(29) Hu Q, Deng X, Kong J*, Dong Y, Liu Q, Zhang X*. Simple and fast electrochemical detection of sequence-specific DNA via click chemistry-mediated labeling of hairpin DNA probes with ethynylferrocene. Analyst, 2015, 140, 4154-4161.

(30) Hu Q, Zhou B, Li F, Kong J*, Zhang X*. Turn‐on colorimetric platform for dual activity detection of acid and alkaline phosphatase in human whole blood. Chem. Asian J., 2016, 11, 3040-3045.

(31) 胡琼*, 李诗琪, 梁伊依, 冯文星, 骆怡琳, 曹晓静, 牛利*. 基于硼酸盐亲和辅助电化学调控ATRP的癌胚抗原超灵敏电化学适体传感研究. 电化学, 2022. DOI: 10.13208/j.electrochem.2218001. (中文核心期刊约稿)

(32) 胡琼, 甘世宇, 包宇, 韩冬雪, 牛利*. 基于可控/“活性”自由基聚合的生物传感分析. 化工进展, 2021, 40, 2710-2718. (中文核心期刊, EI全文收录)

(33) 严铟蕾, 胡琼*, 牛利*. 超分子水凝胶的制备与应用. 材料研究与应用, 2022. 已接收. (中文核心期刊)

(34) Qian Q, Hu Q, Li L, Shi P, Zhou J, Kong J*, Zhang X, Sun G*, Huang W*. Sensitive fiber microelectrode made of nickel hydroxide nanosheets embedded in highly-aligned carbon nanotube scaffold for nonenzymatic glucose determination. Sens. Actuators, B, 2018, 257, 23-28. (co-first author) (TOP期刊)

(35) Mei Y, Hu Q, Zhou B, Zhang Y, He M, Xu T, Li F, Kong J*. Fluorescence quenching based alkaline phosphatase activity detection. Talanta, 2018, 176, 52-58. (co-first author)

(36) Liu Q, Hu Q, Li L, Kong J*, Zhang X*. Click chemistry-based aptasensor for highly sensitive electrochemical detection of thrombin. Anal. Methods, 2017, 9, 3825-3830. (co-first author)

(37) He M, Hu Q, Mei Y, Zhou B, Kong J*, Zhang X. Metal-to-ligand charge-transfer-based visual detection of alkaline phosphatase activity. Anal. Sci., 2018, 34, 341-347. (co-first author)

(38) Qu X, Hu Q, Song Z, Sun Z, Zhang B, Zhong J, Cao X, Liu Y, Zhao B, Liu Z, Shen Y, Bao Y, Wang Z, Zhang Y*, Niu L. Adsorption and desorption mechanisms on graphene oxide nanosheets: Kinetics and tuning. Innovation, 2021, 2, 100137.

(39) Huang P, Zhang B*, Hu Q, Zhao B, Zhu Y, Zhang Y, Kong Y, Zeng Z, Bao Y, Wang W, Cheng Y*, Niu L*. Polymer electrochemiluminescence featuring thermally activated delayed fluorescence. ChemPhysChem, 2021, 22, 726-732.

(40) Zhao B, Luo Y, Qu X, Hu Q, Zou J, He Y, Liu Z, Zhang Y*, Bao Y, Wang W, Niu L*. Graphite-like carbon nitride nanotube for electrochemiluminescence featuring high efficiency, high stability and ultrasensitive ion detection capability. J. Phys. Chem. Lett., 2021, 12, 11191-11198.

(41) 牛利,胡琼. 一种生物学介导的RAFT聚合方法. (发明专利,申请号:202210232483.2)

(42) 牛利,胡琼. 一种糖蛋白的电化学适体检测方法. (发明专利,申请号:202210361907.5)

(43) 牛利,胡琼,曹晓静,骆怡琳,李诗琪,梁伊依,冯文星. 一种糖轭合物的比率型电化学检测方法. (发明专利,申请号:202210664735.9)

(44) 孔金明,胡琼,何玟辉,梅亚琦,张学记. 一种碱性磷酸酶活性的测定方法. (发明专利,专利号:ZL 2015 1 0666268.3)

(45) 孔金明,胡琼,梅亚琦,何玟辉,张学记. 一种酸性磷酸酶活性的测定方法. (发明专利,专利号:ZL 2016 1 0013539.X)

(46) 孔金明,胡伟文,顾淑梅,胡琼,张学记. 一种基于吗啉寡核苷酸功能化硅基芯片的高选择性DNA荧光分析方法. (发明专利,专利号:ZL 2014 1 0745647.7)

(47) 孔金明,胡伟文,顾淑梅,胡琼,张学记. 基于吗啉寡核苷酸功能化磁性微球的高灵敏度DNA荧光分析方法. (发明专利,专利号:ZL 2015 1 0112512.1)

(48) 孔金明,胡伟文,顾淑梅,胡琼,张学记. 基于聚胸腺嘧啶为模板生成铜纳米粒子的高灵敏度DNA荧光分析方法. (发明专利,专利号:ZL 2015 1 0287942.7)

 

其他情况

(1) Anal. Chem.Biosens. Bioelectron.、Sens. Actuators, BAnal. Chim. ActaElectroanalysisSpectrochim. Acta AMicrochem. J.等国际SCI期刊的资深评审专家。

Copyright 广州大学3003必赢贵宾会官方网址版权所有.  地址:广州大学城外环西路230号    邮编:510006