史文静

作者: 时间:2021-03-16 点击数:

博士,讲师,硕士生导师

 

专    业: 化学

研究领域: 有机小分子荧光探针及生物成像

办 公 室: 生化楼624

电子邮件: swj114@gzhu.edu.cn

 

教育经历:

2009.08–2013.07,香港中文大学,化学系,哲学博士学位(化学专业)。导师:Prof. Dennis K. P. Ng

2005.09–2009.07,中国科学技术大学,化学物理系,理学学士学位。导师:张广照 教授

 

工作经历:

2016.01–今,广州大学,3003必赢贵宾会官方网址,讲师

2013.08–2015.12,香港中文大学,化学系,博士后研究员。合作导师:Prof. Dennis K. P. Ng

 

研究方向:

功能有机发光染料的设计合成,氟硼二吡咯,荧光探针,生物成像

 

主要荣誉:

入选2017年广东省“珠江人才计划”青年拔尖人才项目

 

承担项目:

[1] 国家自然科学基金青年项目,主持,2021.01-2023.12

[2] 广东省自然科学基金项目,主持,2018.05-2021.04

[3] 广州市基础研究计划市校(院)联合资助项目,主持,2021.05-2023.04.

[4] 广东省教育厅高等教育创新强校工程-青年创新项目,主持,2017.04-2019.03

[5] 广州市教育局市属高校科研项目-青年项目,主持,2017.01-2018.12

[6] 广州大学启动项目,主持,2016.01–2017.12

[7] 广州大学新苗计划,主持,2016.01–2017.12

 

代表性研究成果:

[1] Wen-Jing Shi*, Yong-Feng Wei, Jinrong Yang, Hui-Zhi Li, Qing-Hui Wan, Yuxuan Wang, Huaxiang Leng, Kun Chen, Jin-wu Yan*, Novel meso-trifluoromethyl BODIPY-based near-infrared-emitting fluorescent probes for organelle-specific imaging of cellular viscosity, Sensors Actuat. B Chem 2022, 359, 131594.

[2] Wen-Jing Shi*, Jinrong Yang, Yongfeng Wei, Xiao-Tong Li, Xu-Hui Yan, Yuxuan Wang, Hua-xiang Leng, Liyao Zheng, Jin-Wu Yan*, Novel cationic meso-CF3 BODIPY-based AIE fluorescent rotors for imaging viscosity in mitochondria, Chem. Commun. 2022, 58, 1930-1933.

[3] Yong-Feng Wei1, Xuan Wang1, Wen-Jing Shi*, Ru Chen, Liyao Zheng, Zi-Zhou Wang, Kun Chen, Liqian Gao*, A Novel Methylenemalononitrile-BODIPY-based Fluorescent Probe for Highly Selective Detection of Hydrogen Peroxide in Living Cells, Eur. J. Med. Chem. 2021, 226, 113828. (获邀在CBG“人物与科研”报道)

[4] Wen-Jing Shi*, Liu-Xia Feng, Xuan Wang, Yan Huang, Yong-Feng Wei, Huai-Jin Ma, Wei Wang, Menghua Xiang, Liqian Gao*, A Near-infrared-emission Aza-BODIPY-based Fluorescent Probe for Fast, Selective, and “Turn-on” Detection of HClO/ClO-, Talanta 2021, 233, 122581.

[5] Yan Huang, Chun-Feng Li, Wen-Jing Shi*, Hui-Ya Tan, Zhi-Zhou He, Liyao Zheng, Fenggang Liu, Jin-Wu Yan*, A Near-Infrared BODIPY-Based Fluorescent Probe for Ratiometric and Discriminative Detection of Hg2+ and Cu2+ Ions in Living Cells. Talanta 2019, 198, 390-397.

[6] Wen-Jing Shi, Jian-Yong Liu, Pui-Chi Lo, Dennis K. P. Ng*, Selective Detection of Hg2+ Ion with Boron Dipyrromethene-Based Fluorescent Probes Appended with a Bis(1,2,3-triazole)amino Receptor. Chem. Asian J. 2019, 14(7), 1059-1065.

[7] Wen-Jing Shi*, Pui-Chi Lo*, Dennis K. P. Ng*, Synthesis and Acid-Responsive Spectral Properties of Near-Infrared-Absorbing Donor-π-Donor-type Aza Boron Dipyrromethenes. Dyes Pigments 2018, 154, 314-319.

[8] Wen-Jing Shi, Pui-Chi Lo*, Shirui Zhao, Roy C. H. Wong, Qiong Wang, Wing-Ping Fong, Dennis K. P. Ng*, A Biotin-Conjugated Glutathione-Responsive FRET-Based Fluorescent Probe with a Ferrocenyl BODIPY as the Dark Quencher. Dalton Trans. 2016, 45, 17798-17806.

[9] Wen-Jing Shi, Roel Menting, Eugeny A. Ermilov, Pui-Chi Lo, Beate Röder, Dennis K. P. Ng*, Formation and Photoinduced Processes of the Host-Guest Complexes of a b-Cyclodextrin-Conjugated Aza-BODIPY and Tetrasulfonated Porphyrins. Chem. Commun. 2013, 49, 5277-5279.

[10] Wen-Jing Shi1, Mohamed E. El-Khouly*,1, Kei Ohkubo1, Shunicih Fukuzumi*, Dennis K. P. Ng*, Photosynthetic Antenna-Reaction-Center Mimicry with a Covalently Linked Monostyryl-Boron Dipyrromethene-Aza-Boron-Dipyrrolmethene-C60 Triad. Chem. Eur. J. 2013, 19, 11332-11341.

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